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Ticlopidine vs Aspirin for Prevention of Recurrent Stroke, Analysis of Pts with Stroke from Ticlopidine Aspirin Study Stroke 23:1723-1727, Harbison,J.W., 1992 See this aricle in Pubmed Article Abstract Minor stroke was the qualifying ischemic event in 927 patients(463 received ticlopidine and 464 received aspirin).The cumulative event rate at 1 year for nonfatal stroke or death was 6.3%for patients receiving ticlopidine and 10.8%for patients receiving aspirin,a 42%risk reduction in favor of ticlopidine.For fatal or nonfatal stroke,the cumulative event rate at 1 year was 4.8%for patients receiving ticlopidine and 7.5%for those receiving aspirin,a risk reduction of 36%for ticlopidine relative to aspirin.The overall risk reductions were 22.1%for nonfatal stroke or death and 19.9%for fatal or nonfatal stroke.Adverse reactions were reported in 58%of the ticlopidine patients and 51%of the aspirin patients.The results in this subgroup are consistent with the overall TASS results and show that ticlopidine is somewhat more effective than aspirin for reducing the risk of stroke in patients with a completed minor stroke.

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(click to filter results - removes previous filter) aspirin cerebrovascular accident cerebrovascular accident,prevention of cerebrovascular accident,recurrent platelet inhibiting drugs ticlopidine treatment of neurologic disorder

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